Peptide Publications Archive
Showing items in Cyclic Peptides · Clear filter
Ultrafast Peptide Cyclization
Sun Lab
Cyclic peptides occupy a privileged niche in chemical biology. Their constrained conformations reduce entropic penalties upon binding, impart proteolytic stability, and frequently enable access to …
Molecular Scaffolds
Craik Lab
This comprehensive review from the labs of David Craik and Lara Malins at Australian Research Council Centre of Excellence for Innovations in Peptide and Protein …
Enlicitide Decanoate
Thaisrivongs Lab
The total synthesis and process development of enlicitide decanoate, MK-0616, an orally bioavailable inhibitor of proprotein convertase subtilisin/kexin type 9, PCSK9, represents a major breakthrough …
Selective Cyclization
Liu Lab
To address the limitations of current methods for peptide macrocyclization, which often rely on nonspecific small-molecule linkers...
Yeast CICLOPPS
Knudsen Lab
Researchers in the Knudsen Group at the University of Aarhus, Denmark, published in Biochemistry, report the construction of a Saccharomyces cerevisiae-specific SICLOPPS library …